Publications | Nathan Skene

Julien Bryois*, Nathan G. Skene*, Thomas Folkmann Hansen, Lisette J.A. Kogelman, Hunna J. Watson, Eating Disorders Working Group of the Psychiatric Genomics Consortium, International Headache Genetics Consortium,, The 23andMe Research Team, Leo Brueggeman, Gerome Breen, Cynthia M. Bulik, Ernest Arenas, Jens Hjerling-Leffler, Patrick F. Sullivan (2019). Genetic Identification of Cell Types Underlying Brain Complex Traits Yields Novel Insights Into the Etiology of Parkinson's Disease. bioRxiv.

PDF

I Jansen, J Savage, K Watanabe, J Bryois, D Williams, S Steinberg, J Sealock, I Karlsson, S Hagg, L Athanasiu, N Voyle, P Proitsi, A Witoelar, S Stringer, D Aarsland, I Almdahl, F Andersen, S Bergh, F Bettella, S Bjornsson, A Braekhus, G Brathen, C Leeuw, R Desikan, S Djurovic, L Dumitrescu, T Fladby, T Homan, P Jonsson, A Rongve, I Saltvedt, S Sando, G Selbak, N Skene, J Snaedal, E Stordal, I Ulstein, Y Wang, L White, J Hjerling-Leffler, P Sullivan, W van der Flier, R Dobson, L Davis, H Stefansson, K Stefansson, N Pedersen, S Ripke, O Andreassen, D Posthuma (2019). Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk. NatGen.

PDF

Xiaoyan Qian, Kenneth D Harris, Thomas Hauling, Dimitris Nicoloutsopoulos, Ana Munoz Manchado, Nathan Skene, Jens Hjerling-Leffler, Mats Nilsson (2018). A spatial atlas of inhibitory cell types in mouse hippocampus. bioRxiv.

PDF

A Muñoz-Manchado, C Gonzales, A Zeisel, H Munguba, B Bekkouche, N Skene, P Lönnerberg, J Ryge, K Harris, S Linnarsson, J Hjerling-Leffler (2018). Diversity of Interneurons in the Dorsal Striatum Revealed by Single-Cell RNA Sequencing and PatchSeq. Cell Reports.

PDF

Amit Zeisel, Hannah Hochgerner, Peter Lonnerberg, Anna Johnsson, Fatima Memic, Job van der Zwan, Martin Haring, Emelie Braun, Lars Borm, Gioele La Manno, Simone Codeluppi, Alessandro Furlan, Nathan Skene, Kenneth D Harris, Jens Hjerling Leffler, Ernest Arenas, Patrik Ernfors, Ulrika Marklund, Sten Linnarsson (2018). Molecular architecture of the mouse nervous system. Cell.

PDF

F Zhu, M Cizeron, Z Qiu, R Benavides-Piccione, M Kopanitsa, N Skene, J DeFelipe, E Fransén, N Komiyama, S Grant (2018). Architecture of the Mouse Brain Synaptome. Neuron.

PDF

Mats Nagel, Philip R. Jansen, Sven Stringer, Kyoko Watanabe, Christiaan A. de Leeuw, Julien Bryois, Jeanne E. Savage, Anke R. Hammerschlag, Nathan G. Skene, Ana B. Muñoz-Manchado, 23andMe Research Team, Tonya White, Henning Tiemeier, Sten Linnarsson, Jens Hjerling-Leffler, Tinca J. C. Polderman, Patrick F. Sullivan, Sophie van der Sluis & Danielle Posthuma (2018). Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. Nature Genetics.

PDF

Jeanne E. Savage, Philip R. Jansen, Sven Stringer, Kyoko Watanabe, Julien Bryois, Christiaan A. de Leeuw, Mats Nagel, Swapnil Awasthi, Peter B. Barr, Jonathan R. I. Coleman, Katrina L. Grasby, Anke R. Hammerschlag, Jakob A. Kaminski, Robert Karlsson, Eva Krapohl, Max Lam, Marianne Nygaard, Chandra A. Reynolds, Joey W. Trampush, Hannah Young, Delilah Zabaneh, Sara Hägg, Narelle K. Hansell, Ida K. Karlsson, Sten Linnarsson, Grant W. Montgomery, Ana B. Muñoz-Manchado, Erin B. Quinlan, Gunter Schumann, Nathan G. Skene, Bradley T. Webb, Tonya White, Dan E. Arking, Dimitrios Avramopoulos, Robert M. Bilder, Panos Bitsios, Katherine E. Burdick, Tyrone D. Cannon, Ornit Chiba-Falek, Andrea Christoforou, Elizabeth T. Cirulli, Eliza Congdon, Aiden Corvin, Gail Davies, Ian J. Deary, Pamela DeRosse, Dwight Dickinson, Srdjan Djurovic, Gary Donohoe, Emily Drabant Conley, Johan G. Eriksson, Thomas Espeseth, Nelson A. Freimer, Stella Giakoumaki, Ina Giegling, Michael Gill, David C. Glahn, Ahmad R. Hariri, Alex Hatzimanolis, Matthew C. Keller, Emma Knowles, Deborah Koltai, Bettina Konte, Jari Lahti, Stephanie Le Hellard, Todd Lencz, David C. Liewald, Edythe London, Astri J. Lundervold, Anil K. Malhotra, Ingrid Melle, Derek Morris, Anna C. Need, William Ollier, Aarno Palotie, Antony Payton, Neil Pendleton, Russell A. Poldrack, Katri Räikkönen, Ivar Reinvang, Panos Roussos, Dan Rujescu, Fred W. Sabb, Matthew A. Scult, Olav B. Smeland, Nikolaos Smyrnis, John M. Starr, Vidar M. Steen, Nikos C. Stefanis, Richard E. Straub, Kjetil Sundet, Henning Tiemeier, Aristotle N. Voineskos, Daniel R. Weinberger, Elisabeth Widen, Jin Yu, Goncalo Abecasis, Ole A. Andreassen, Gerome Breen, Lene Christiansen, Birgit Debrabant, Danielle M. Dick, Andreas Heinz, Jens Hjerling-Leffler, M. Arfan Ikram, Kenneth S. Kendler, Nicholas G. Martin, Sarah E. Medland, Nancy L. Pedersen, Robert Plomin, Tinca J. C. Polderman, Stephan Ripke, Sophie van der Sluis, Patrick F. Sullivan, Scott I. Vrieze, Margaret J. Wright & Danielle Posthuma (2018). Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence. Nature Genetics.

PDF

Kenneth D Harris, Hannah Hochgerner, Nathan G Skene, Lorenza Magno, Linda Katona, Carolina Bengtsson Gonzales, Peter Somogyi, Nicoletta Kessaris, Sten Linnarsson, Jens Hjerling-Leffler (2018). Classes and continua of hippocampal CA1 inhibitory neurons revealed by single-cell transcriptomics. PLoS biology.

PDF

Nathan G. Skene, Julien Bryois, Trygve E. Bakken, Gerome Breen, James J Crowley, Héléna A Gaspar, Paola Giusti-Rodriguez, Rebecca D Hodge, Jeremy A. Miller, Ana Muñoz-Manchado, Michael C O’Donovan, Michael J Owen, Antonio F Pardiñas, Jesper Ryge, James T R Walters, Sten Linnarsson, Ed S. Lein, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Patrick F Sullivan, Jens Hjerling-Leffler (2018). Genetic identification of brain cell types underlying schizophrenia. Nature Genetics.

Preprint PDF

Jonathan R. I. Coleman, Julien Bryois, Héléna A. Gaspar, Philip R. Jansen, Jeanne E. Savage, Nathan Skene, Robert Plomin, Ana B. Muñoz-Manchado, Sten Linnarsson, Greg Crawford, Jens Hjerling-Leffler, Patrick F. Sullivan, Danielle Posthuma, Gerome Breen (2018). Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals. Molecular Psychiatry.

PDF

Philip R Jansen, Kyoko Watanabe, Sven Stringer, Nathan Skene, Julien Bryois, Anke R Hammerschlag, Chrstiaan A de Leeuw, Jeroen Benjamins, Ana B Munoz-Manchado, Mats Nagel, Jeanne E Savage, Henning Tiemeier, Tonya White, Joyce Y Tung, David A Hinds, Vladimir Vacic, Patrick F Sullivan, Sophie van der Sluis, Tinca JC Polderman, August B Smit, Jens Hjerling-Leffler, Eus JW van Someren, Danielle Posthuma (2018). Genome-Wide Meta-Analysis of Insomnia Complaints (N=1,331,010) Identifies Novel Genetic Loci and Functional Pathways. bioRxiv.

PDF

Marcia Roy, Oksana Sorokina, Nathan Skene, Clémence Simonnet, Francesca Mazzo, Ruud Zwart, Emanuele Sher, Colin Smith, J. Douglas Armstrong, Seth G. N. Grant (2017). Proteomic analysis of postsynaptic proteins in regions of the human neocortex. Nature Neuroscience.

PDF

Nathan G Skene, Marcia Roy, Seth GN Grant (2017). A genomic lifespan program that reorganises the young adult brain is targeted in schizophrenia. eLife.

PDF

Nathan G Skene, Seth GN Grant (2016). Identification of Vulnerable Cell Types in Major Brain Disorders Using Single Cell Transcriptomes and Expression Weighted Cell Type Enrichment. Frontiers in Neuroscience.

PDF

Anna E Skrzypiec, Rahul S Shah, Emanuele Schiavon, Eva Baker, Nathan Skene, Robert Pawlak, Mariusz Mucha (2013). Stress-induced lipocalin-2 controls dendritic spine formation and neuronal activity in the amygdala. PLoS One.

PDF

Marcelo P. Coba, Noboru H. Komiyama, Jess Nithianantharajah, Maksym V. Kopanitsa, Tim Indersmitten, Nathan G. Skene, Ellie J. Tuck, David G. Fricker, Kathryn A. Elsegood, Lianne E. Stanford, Nurudeen O. Afinowi, Lisa M. Saksida, Timothy J. Bussey, Thomas J. O’Dell, Seth G.N. Grant (2012). TNiK Is Required for Postsynaptic and Nuclear Signaling Pathways and Cognitive Function. Journal of Neuroscience.

PDF